Gregory Maniero

Gregory Maniero

Professor of Biology

gmaniero@stonehill.edu
508-565-1729
Shields 210
Biology

Biography

Gregory Maniero joined the Stonehill College community in 2004. His research interests include comparative immunology, innate immune responses, adaptive immunity and CD4-IL-16 interactions. He studied amphibian immunology while pursuing a bachelor’s degree at the University of Wisconsin. He then completed work focused on immune function in hibernating ground squirrels as a graduate student at the University of Colorado. As a post-doctoral associate at the University of Rochester School of Medicine and Dentistry, he conducted research on amphibian immunology. At this time, he also taught human biology at Monroe Community College. 

Maniero previously worked as a zookeeper. He has also held roles with animal and cellular toxicology labs, a fisheries consulting firm and an AIDS clinical trial laboratory. 

Education

  • B.S, Life Sciences, University of Wisconsin 
  • Ph.D., Department of Environmental, Population, and Organismic Biology, University of Colorado
  • Post-Doctoral Training, University of Rochester School of Medicine and Dentistry

Courses Taught

  • Immunology
  • Vertebrate Physiology
  • Comparative Vertebrate Anatomy
  • Parasitology
  • Adaptations to the Environment
  • Environmental Science
  • Human Anatomy & Physiology Labs
  • Biology 101 & 102 Labs

Selected Publications, Articles & Presentations

  • Maniero, G.D., (2021) Evolutionary conservation of the role of CD4 as a receptor for Interleukin 16. Interleukin. In: Interleukins: The Immune and Non-Immune Systems’ Related Cytokines. P. Behzadi, ed. Chapter 2. IntertechOpen Limited, London. ISBN:978-1-83969-099-0 DOI:10.5772/intechopen.96951
  • Kopec, A.L., Z.E. Michaud, G.D. Maniero (2020) The Role Of IL-16 As a lymphocyte attractant appears to be conserved through phylogeny: Preliminary evidence that recombinant human IL-16 preferentially attracts regulatory lymphocytes in the amphibian, Xenopus laevis. Arch. Autoimmune Dis. 1(2): 44-48.
  • Gillis, J., T.P. Uccello, Z. Magri, N. Morris, G.D. Maniero. (2020) Preliminary indications that recombinant Human IL-16 attracts and stimulates lymphocytes of the amphibian, Xenopus laevis implying an ancestral role for CD4 as a cytokine receptor. Cytokine. 136:155254.
  • Inglis, J.E., K.A. Radziwon, G.D. Maniero. (2008) The Serum Complement System: A Simplified Laboratory Exercise to Measure the Activity of an Important Component of the Immune System. Adv. Physiol. Educ. 32(4):317-321.
  • Robert, J., T. Ramanayake, G.D. Maniero, H. Morales, A. Sima Chida. (2008) Phylogenetic conservation of glycoprotein 96 ability to interact with CD91 and facilitate antigen crosspresentation. J. Immunol. 180(5): 3176-3182
  • Maniero, G.D., H. Morales, J. Gantress, J. Robert. (2006) Generation of a long-lasting,protective, and neutralizing antibody response to the ranavirus FV3 by the frog Xenopus. Dev. Comp Immunol. 30(7):649-657.
  • Maniero, G.D. (2005) Ground squirrel splenic macrophages bind lipopolysaccharide over a wide range of temperatures at all phases of their annual hibernation cycle. J. Comp. Immunol. Microbiol. and Inf. Dis. 28(4): 297-309.
  • Marr, S., A. Goyos, G.D. Maniero, J. Robert. (2005) CD91 up-regulates upon immune stimulation in Xenopus adult but not larval peritoneal leukocytes. Immunogenetics 56: 735-742.
  • Maniero, G.D., J. Robert. (2004) Phylogenic conservation of gp96-mediated antigenspecific cellular immunity: New evidence from adoptive transfer in Xenopus. Transplantation 78(10):1415-1421.
  • Robert J., G.D. Maniero, A. Bell, J. Gantress. (2004). Xenopus as a model system to study evolution of HSP-Immune System Interactions. Methods 32:42-53
  • 2006:  International Society for Developmental and Comparative Immunology 10th International Congress, Charleston, SC.  New England Immunology Conference, Woods Hole, MA. Generation of a long-lasting, protective, and neutralizing antibody response to the ranavirus FV3 by the frog Xenopus. Maniero, G.D., Morales, H., Gantress, J., Robert, J.
  • 2006: FrogLog (June), Newsletter of the Declining Amphibian Task Force.  Progress Report: Detection of the antibody response in northern leopard frogs (Rana pipiens) by ELISA using reagents developed in Xenopus. Schell, R.T., Maniero, G.D.
  • 2006: Eastern New England Biology Conference, Boston, MA  Detection of the antibody response in northern leopard frogs (Rana pipiens) by ELISA using reagents developed in Xenopus. Schell, R.T., Maniero, G.D.

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